Olivier Devuyst Selected Research

Uromodulin

5/2022	Uromodulin and its association with urinary metabolites: the German Chronic Kidney Disease Study.
1/2022	Genome-wide studies reveal factors associated with circulating uromodulin and its relationships to complex diseases.
12/2021	Mendelian randomization to assess causality between uromodulin, blood pressure and chronic kidney disease.
10/2021	Uromodulin: Roles in Health and Disease.
1/2020	Circulating Uromodulin and Risk of Cardiovascular Events and Kidney Failure.
1/2020	Architecture and function of human uromodulin filaments in urinary tract infections.
12/2019	The Urinary Excretion of Uromodulin is Regulated by the Potassium Channel ROMK.
10/2018	Uromodulin is expressed in the distal convoluted tubule, where it is critical for regulation of the sodium chloride cotransporter NCC.
12/2017	A novel homozygous UMOD mutation reveals gene dosage effects on uromodulin processing and urinary excretion.
9/2017	Uromodulin: from physiology to rare and complex kidney disorders.

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Olivier Devuyst Research Topics

Disease

36	Autosomal Dominant Polycystic Kidney (ADPKD) 01/2022 - 12/2000
19	Kidney Diseases (Kidney Disease) 01/2022 - 08/2010
18	Cysts 01/2020 - 12/2000
16	Renal Insufficiency (Renal Failure) 11/2021 - 11/2003
14	Dent Disease 10/2020 - 04/2003
12	Chronic Renal Insufficiency 05/2022 - 05/2010
12	Hypertension (High Blood Pressure) 01/2022 - 12/2007
10	Proteinuria 11/2020 - 04/2003
9	Chronic Kidney Failure (Chronic Renal Failure) 11/2021 - 04/2010
9	Disease Progression 04/2021 - 05/2003
8	Gitelman Syndrome 11/2022 - 03/2007
8	Cystinosis 01/2022 - 04/2010
8	Fibrosis (Cirrhosis) 11/2020 - 10/2001
8	Acidosis 01/2018 - 11/2008
8	Peritonitis 07/2017 - 11/2002
6	Polycystic Kidney Diseases (Polycystic Kidney Disease) 01/2022 - 05/2011
6	Urinary Tract Infections (Urinary Tract Infection) 10/2021 - 10/2016
6	Kidney Calculi (Kidney Stone) 11/2020 - 01/2017
5	Fanconi Syndrome (Syndrome, Fanconi) 01/2020 - 07/2006
5	Nephrogenic Diabetes Insipidus 07/2016 - 04/2002
5	Renal Tubular Acidosis (Distal Renal Tubular Acidosis) 02/2013 - 11/2005
5	Cystic Fibrosis (Mucoviscidosis) 12/2011 - 12/2000
4	Alkalosis 01/2021 - 03/2007
4	Oculocerebrorenal Syndrome (Lowe Syndrome) 10/2020 - 10/2010
4	Lysosomal Storage Diseases (Lysosomal Storage Disease) 01/2020 - 05/2014
4	Infections 08/2014 - 05/2010
3	Bartter Syndrome (Syndrome, Bartter) 11/2022 - 11/2006
3	Body Weight (Weight, Body) 04/2021 - 11/2013
3	Hypercalciuria 11/2020 - 04/2003
3	Methylmalonic acidemia 01/2020 - 01/2016
3	Hyperaldosteronism (Conn Syndrome) 02/2019 - 11/2006
3	Glycosuria 01/2017 - 11/2013
3	Albuminuria 11/2016 - 11/2010
3	Uremia 11/2011 - 10/2001
2	Cardiovascular Diseases (Cardiovascular Disease) 10/2021 - 11/2015
2	Hypokalemia 01/2021 - 02/2019
2	Dent Disease 2 10/2020 - 08/2015
2	Mitochondrial Diseases (Mitochondrial Disease) 04/2020 - 01/2020
2	Gout 10/2019 - 02/2013
2	Stroke (Strokes) 01/2018 - 09/2015

Drug/Important Bio-Agent (IBA)

24	UromodulinIBA 05/2022 - 11/2003
20	Tolvaptan FDA Link 01/2022 - 05/2011
17	Proteins (Proteins, Gene)FDA Link 01/2022 - 02/2002
14	TEMPOIBA 01/2022 - 05/2011
12	SaltsIBA 01/2021 - 03/2007
12	Uric Acid (Urate)IBA 11/2020 - 11/2003
11	Vasopressins (Vasopressin)IBA 01/2019 - 06/2007
11	Chloride Channels (Chloride Channel)IBA 04/2009 - 12/2000
10	CreatinineIBA 11/2019 - 05/2011
9	Vasopressin Receptors (Arginine Vasopressin Receptor)IBA 01/2022 - 06/2007
9	AcidsIBA 01/2021 - 05/2005
9	ChloridesIBA 01/2020 - 09/2002
8	Biomarkers (Surrogate Marker)IBA 01/2019 - 05/2011
6	Pharmaceutical PreparationsIBA 01/2022 - 05/2010
6	Cystine (L-Cystine)IBA 11/2021 - 04/2010
6	SodiumIBA 04/2021 - 02/2005
6	AlbuminsIBA 11/2019 - 11/2010
6	Glucose (Dextrose)FDA LinkGeneric 01/2019 - 12/2003
6	Nitric Oxide (Nitrogen Monoxide)FDA Link 07/2017 - 05/2003
6	Nitric Oxide Synthase (NO Synthase)IBA 01/2010 - 10/2001
5	Phosphates (Orthophosphate)IBA 11/2022 - 01/2011
5	CalciumIBA 11/2022 - 04/2003
5	ElectrolytesIBA 01/2018 - 11/2006
5	Protons (Proton)IBA 01/2017 - 02/2010
4	Low Density Lipoprotein Receptor-Related Protein-2IBA 11/2020 - 04/2010
4	Phosphatidylinositols (Phosphatidylinositol)IBA 10/2020 - 10/2010
4	Methylmalonyl-CoA MutaseIBA 04/2020 - 01/2016
4	Biological ProductsIBA 12/2017 - 02/2012
4	Cystic Fibrosis Transmembrane Conductance Regulator (Protein, CFTR)IBA 04/2009 - 12/2000
3	Amino Acids FDA Link 10/2020 - 01/2011
3	Aquaporins (Water Channels)IBA 10/2020 - 05/2014
3	Urea (Carbamide)FDA LinkGeneric 10/2018 - 12/2003
3	ThiazidesIBA 07/2016 - 10/2008
3	intrinsic factor-cobalamin receptorIBA 05/2016 - 03/2007
3	Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)IBA 10/2015 - 12/2003
3	TRPP Cation ChannelsIBA 07/2013 - 05/2003
3	Arginine Vasopressin (Argipressin)IBA 11/2012 - 04/2002
3	Protein Isoforms (Isoforms)IBA 01/2010 - 10/2001
2	Cysteamine (Mercaptamine)FDA Link 11/2021 - 01/2020
2	Antihypertensive Agents (Antihypertensives)IBA 04/2021 - 01/2018
2	BilirubinIBA 12/2020 - 11/2017
2	CollagenIBA 11/2020 - 10/2015
2	LipidsIBA 10/2020 - 01/2020
2	Adenosine Monophosphate (AMP)IBA 01/2020 - 07/2013
2	EnzymesIBA 01/2020 - 06/2004
2	DNA (Deoxyribonucleic Acid)IBA 01/2020 - 01/2018
2	Gentamicins (Gentamicin)FDA LinkGeneric 01/2020 - 12/2011
2	ReninIBA 02/2019 - 10/2015
2	Bicarbonates (Hydrogen Carbonate)IBA 02/2019 - 09/2014
2	Inositol Polyphosphate 5-PhosphatasesIBA 01/2019 - 08/2015
2	MagnesiumIBA 01/2019 - 03/2011
2	Furosemide (Lasix)FDA LinkGeneric 10/2018 - 02/2015
2	Sodium Chloride FDA LinkGeneric 10/2018 - 04/2007
2	Messenger RNA (mRNA)IBA 01/2018 - 10/2009
2	Transaminases (Aminotransferases)IBA 11/2017 - 01/2016

Therapy/Procedure

13	Peritoneal Dialysis 11/2021 - 12/2003
7	Therapeutics 11/2021 - 03/2005
4	Transplantation 01/2017 - 07/2010
4	Renal Replacement Therapy (Therapies, Renal Replacement) 07/2015 - 05/2014
2	Treatment Delay 01/2018 - 01/2017